• In the tissues of a tiny worm, a close-up view of where genes are working

    Tuesday, Sep 25, 2018
    by Molly Sharlach, School of Engineering and Applied Science

    Scientists have long prized the roundworm Caenorhabditis elegans as a model for studying the biology of multicellular organisms. The millimeter-long worms are easy to grow in the lab and manipulate genetically, and they have only around 1,000 cells, making them a powerful system for probing intricacies of development, behavior and metabolism.

  • Chemist Car wins DOE funding for computational chemistry center

    Thursday, Sep 20, 2018
    by Liz Fuller-Wright, Office of Communications

    The U.S. Department of Energy (DOE) announced Wednesday, Sept. 19, that Roberto Car, Princeton’s Ralph W. *31 Dornte Professor in Chemistry and a professor with the Princeton Institute for the Science and Technology of Materials, was one of 10 researchers to win funding for computational chemistry. His proposal title was “Computational Chemical Science Center: Chemistry in Solution and at Interfaces.”

  • The spotlight of attention is more like a strobe, say researchers

    Wednesday, Aug 22, 2018
    by Liz Fuller-Wright, Office of Communications

    You don’t focus as well as you think you do.

    That’s the fundamental finding of a team of researchers from Princeton University and the University of California-Berkeley who studied monkeys and humans and discovered that attention pulses in and out four times per second.

  • MacMillan lab finds new way to bond molecules that could speed drug discovery

    Monday, Aug 6, 2018
    by by Amy Carleton

    Bringing new drugs to market takes time. Laboratory testing, clinical research and U.S. Food and Drug Administration review — and all the steps in between — add up to 17 years, on average, for research evidence to reach clinical practice.

    But what if organic chemists could speed up that process by providing medicinal chemists with new tools that would facilitate selective molecule activation to support drug discovery?

  • Timing is key for bacteria surviving antibiotics

    Monday, Jul 2, 2018
    by Molly Sharlach, Office of Engineering Communications

    For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth had a much better chance of surviving treatment.

    When antibiotics hit a population of bacteria, often a small fraction of “persister” cells survive to pose a threat of recurrent infection. Unlike bacteria with genetic resistance to antibiotics, evidence suggests that persisters stay alive in part by stalling cellular processes targeted by the drugs.

  • Petry finds missing ingredient to spark the fireworks of life

    Wednesday, May 16, 2018
    by Liz Fuller-Wright, Office of Communications

    Most people can name at least a few bones of the human body, but not many know about the cytoskeleton within our cells, let alone the “microtubules” that give it its shape. Now, a group of Princeton researchers has resolved a long-standing controversy by identifying exactly how the body creates these micron-sized filaments.

  • Princeton Research Day puts spotlight on innovative work across University

    Monday, May 14, 2018
    by Princeton University

    Spend the day — or an hour — at Princeton Research Day, and you get an eclectic tour of research at Princeton University shared through presentations designed to make cutting-edge work accessible to the general public.

    For Sarah-Jane Leslie, dean of the Graduate School and the Class of 1943 Professor of Philosophy, that tour included learning how engineers can learn lessons from plants; about new techniques to fight disease; and about novel ways to address the world’s energy crisis.


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