Regional Academic Drug Discovery Day 2019

Fri, Nov 1, 2019, 8:00 am
Location: 
Sponsor(s): 
New Jersey Academic Drug Discovery Consortium
Princeton University Dean for Research. Office of Corporate Engagement and Office of Technology Licensing

Save the Date: Join us for the Third Annual Regional Academic Drug Discovery Conference

More than 200 stakeholders in drug discovery from industry, academia and government will come together on the Princeton University campus for a full day of programming. (Check out the program at last year's event hosted by Rutgers.)


2019 Keynote

Barry R. O'Keefe, Ph.D.  Acting Chief, Molecular Targets Program  Center for Cancer Research  Chief, Natural Products Branch, Developmental Therapeutics Program  Division of Cancer Treatment and Diagnosis  National Ca

Barry R. O'Keefe, Ph.D.

Acting Chief, Molecular Targets Program

Center for Cancer Research

Chief, Natural Products Branch, Developmental Therapeutics Program

Division of Cancer Treatment and Diagnosis

National Cancer Institute

Natural Product-based Drug Discovery: Why, How and Is Now the Time?

Natural products have a proven track record in use as anti-cancer and anti-infective agents. As of 2014 natural products (NP), NP pharmacophores, and NP mimics represented more than 50 percent of small molecule-based anti-cancer and anti-microbial drugs. However, accessing the potential of NPs in high-throughput screening (HTS) campaigns has been challenging due to the complexity of the crude NP extracts, the time necessary for follow-up isolation efforts, and indefinite capabilities for large-scale resupply. This has resulted in NP-based libraries being significantly underrepresented in most recent large-scale HTS programs.

The US National Cancer Institute’s Natural Product Extract Repository is one of the world’s largest, most diverse collections of natural products containing over 230,000 unique extracts derived from plant, marine and microbial organisms. To address the challenges in screening NPs and encourage increased assay of NP chemical diversity, we have initiated the NCI Program for Natural Product Discovery (NPNPD) which has developed an automated, high-throughput robotics platform capable of generating a library of >1,000,000 partially purified extracts for screening. In addition, automated secondary purification and structure elucidation platforms have been created that significantly decrease costs and timelines. This presentation will discuss the reasons for, challenges to, and mechanisms by which to increase the pace and efficiency of NP-based drug discovery.

National Cancer Institute Natural Products Repository


November 1, 2019, 8am-5pm

McDonnell Hall, Princeton University

New Jersey Academic Drug Discovery Consortium.

Hosted by

Princeton University


Sponsorship Opportunities

Dean Edelman, dean.edelman@princeton.edu, 609-258-6214

Laurie Tzodikov, tzodikov@princeton.edu, 609-258-7256

RADD Sponsorship Information


Call for Abstracts of Presentations

Deadline to submit an presentation abstract for consideration: September 20, 2019.

Submission guidelines and form are found here.


Poster Reservations and Information

Deadline to submit a poster abstract for consideration: October 15, 2019.

Submission guidelines and form are found here

Maximum poster size:  4' x 4' 

For more information, contact Troy Messick, tmessick@wistar.org


Attendee Information

Hotel and Transportation Information

Travel and lodging info for visitors to the Princeton campus

Lodging info from VisitPrinceton.org, the Princeton Mercer Convention & Visitors Bureau

There are no negotiated discounts for travel or lodging related to this conference. 
 

Ticketing Information

Please complete this form to receive more information and an invitation to attend when tickets are available.

Categories: General Event